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The Big Breakfast Study: Chrono-nutrition influence on energy expenditure and bodyweight

Ruddick-Collins, L, Johnston, Jonathan, Morgan, P and Johnstone, A (2018) The Big Breakfast Study: Chrono-nutrition influence on energy expenditure and bodyweight Nutrition Bulletin, 43 (2). pp. 174-183.

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A growing body of evidence highlights the importance of the biological clock as a modulator of energy balance and metabolism. Recent studies in humans have shown that ingested calories are apparently utilised more efficiently in the morning than in the evening and this is manifest through improved weight loss, even under iso-energetic calorie intake. The mechanisms behind this enhanced morning energy metabolism are not yet clear, although it may result from behavioural adaptations or circadian driven variations in physiology and energy metabolism. A major objective of the newly funded Big Breakfast Study, therefore, is to investigate the mechanistic basis of this amplified morning thermogenesis leading to enhanced weight loss, by exploring behavioural and physiological adaptations in energy expenditure alongside the underlying circadian biology. This report briefly discusses the current research linking meal timing, circadian rhythms and metabolism; highlights the research gaps; and provides an overview of the studies being undertaken as part of the Medical Research Council funded Big Breakfast Study.

Item Type: Article
Divisions : Faculty of Health and Medical Sciences > School of Biosciences and Medicine
Authors :
Ruddick-Collins, L
Morgan, P
Johnstone, A
Date : 8 May 2018
Funders : Medical Research Council (MRC)
DOI : 10.1111/nbu.12323
Copyright Disclaimer : © 2018 The Authors. Nutrition Bulletin published by John Wiley & Sons Ltd on behalf of British Nutrition Foundation This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Uncontrolled Keywords : Weight loss; Chrono-nutrition; Breakfast; Energy balance; Meal timing; Circadian rhythms
Depositing User : Melanie Hughes
Date Deposited : 10 Apr 2018 12:30
Last Modified : 02 Aug 2019 13:02

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